NOT FOR INTRATHECAL USE

• Pediatric angio cardiography
• Selective coronary arteriography with or without left ventriculography
• Peripheral arteriography
• Aortography
• Selective visceral arteriography
• Cerebral angiography
• Intra-arterial digital substraction angiography
• Intravenous digital subtraction angiography
• Peripheral venography (phlebography)
• Excretory urography
• Contrast enhancement of computed tomographic head and body imaging
• Arthrography
• Hysterosalpinography

PACKAGING
Hexabrix® 320 (ioxaglate) Injection, 320 mgI/mL

• 50 mL in cartons of 25 single dose vials.
• 100 mL, 200 mL in cartons of 12 single dose bottles.

PRESCRIBING INFORMATION
For complete information on Hexabrix® please refer to the full Prescribing Information . For additional product related questions, please contact a Medical Liaison.

WARNINGS
Ionic iodinated contrast media inhibit blood coagulation, in vitro, more than nonionic contrast media.
Hexabrix® is contraindicated for use in myelography. 
Serious adverse reactions have been reported due to the inadvertent intrathecal administration of iodinated contrast media that are not indicated for intrathecal use. These serious adverse reactions include: death, convulsions, cerebral hemorrhage, coma, paralysis, arachnoiditis, acute renal failure, cardiac arrest, seizures, rhabdomyolysis, hypothermia and brain edema. Special attention must be given to insure that this drug product is not administered intrathecally. Severe, life threatening anaphylactoid reactions, mostly of the cardiovascular origin have occurred following the administration of Hexabrix® as well as other iodine containing contrast agents. The most frequent adverse reactions are nausea, vomiting, facial flush and a feeling of body warmth. These are usually of brief duration. In double-blind clinical trials, Hexabrix® produced less discomfort upon injection (pain and heat) when compared to various other contrast agents.
Please see accompanying full Prescribing Information.

ORDERING INFORMATION
For U.S. customers only. To request a sample or to order products please contact a Medical Center Professional. Please contact Guerbet Corporate office or an appropriate subsidiary if you are located outside the U.S.

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